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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T38969 | Factor B-IN-1 | ||
Factor B-IN-1 is a Factor B inhibitor. | |||
T4376 | Nampt-IN-1 | LSN3154567 | c-Fms , NAMPT , CSF-1R |
Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM. | |||
T4182 | Lavendustin B | Tyrosinase , transporter , HIV Protease | |
Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75). | |||
T6429 | Caffeic Acid Phenethyl Ester | Phenylethyl Caffeate,CAPE | Apoptosis , NF-κB |
Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective... | |||
TWS1977 | Kamebakaurin | Kamebakaurine | NF-κB |
1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression... | |||
T6S1256 | Ruscogenin | NOS , NF-κB , NOD-like Receptor (NLR) | |
1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein ... | |||
T62688 | Factor B-IN-4 | ||
Factor B-IN-4 is a potent inhibitor (IC50: 1 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases. | |||
T82616 | Dalcinonacog alfa | CB-2679d,ISU-304,DalcA | |
Dalcinonacog alfa, a recombinant factor IX (FIX), is utilized in the research of Hemophilia B [1]. | |||
T81655 | Nonacog alfa | BAX326,Coagulation Factor IX [Recombinant] | |
Nonacog alfa (BAX326), a recombinant human factor IX, is utilized in the study of hemophilia B [1]. | |||
T27033 | CKD-712 | CKD 712,CKD712 | |
CKD-712 is a nuclear factor NF-kappa B inhibitor. CKD-712 suppressed MMP-9, but not MMP-2 and other NF-κB-regulated proteins involved in cancer metastasis such as VEGF. CKD-712 induced cell cycle arrest at G2M phase by s... | |||
T76921 | Befovacimab | ||
Befovacimab (BAY 1093884), a fully human monoclonal IgG2 antibody, binds to the tissue factor pathway inhibitor (TFPI). It is utilized in research for haemophilia A/B [1]. | |||
T75485 | Dehydrobruceine B | ||
Dehydrobruceine B, a quassinoid isolated from Brucea javanica, demonstrates a synergistic effect with Cisplatin in inducing apoptosis through the mitochondrial pathway. It enhances the expression of apoptosis-inducing fa... | |||
T76277 | Vosoritide | ||
Vosoritide (BMN 111), a modified recombinant C-type natriuretic peptide (CNP) analogue, engages with natriuretic peptide receptor type B (NPR-B) to diminish the function of fibroblast growth factor receptor 3 (FGFR3). Th... | |||
T74683 | IONIS-FB-LRx | ||
IONIS-FB-LRx, a targeted antisense oligonucleotide (ASO) specifically designed to inhibit complement factor B (CFB), effectively lowers circulating CFB levels. This compound has potential applications in geographic atrop... | |||
T73120 | MptpB-IN-1 | ||
MptpB-IN-1 is a potent, orally active MptpB inhibitor that targets the Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB), a secreted virulence factor evading host antimicrobial mechanisms. It effectively ... | |||
T77188 | Tifcemalimab | ||
Tifcemalimab (JS004), a humanized monoclonal antibody targeting BTLA (B and T lymphocyte attenuation factor), inhibits the HVEM-BTLA interaction by binding to BTLA. This action prevents the BTLA-mediated inhibitory signa... | |||
T76043 | S961 TFA | ||
S961 TFA is a highly selective and high-affinity antagonist of the insulin receptor (IR), demonstrating IC50 values of 0.048 nM for HIR-A, 0.027 nM for HIR-B, and 630 nM for the human insulin-like growth factor I recepto... | |||
T76043L | S961 acetate | ||
S961 acetate is a selective and high-affinity antagonist of the insulin receptor (IR), demonstrating IC50 values of 0.048 nM for HIR-A, 0.027 nM for HIR-B, and 630 nM for the human insulin-like growth factor I receptor (... | |||
T76814 | Lampalizumab | ||
Lampalizumab (RG 7417), a humanized monoclonal antibody, selectively inhibits complement Factor D in the alternative complement pathway by binding to an exosite and sterically hindering Factor B's access to the active si... | |||
T36439 | Gramicidin A | Antibacterial , HIF , Parasite | |
Gramicidin A is a peptide antibiotic isolated from B. brevis.Gramicidin A is a highly hydrophobic channel-forming ion carrier that forms monovalent cation-permeable channels in artificial membranes.Gramicidin A induces t... |